The Holloway in Holywell Lake is partially blocked due to a crash around Farthing Down near Holywell Inn.
This is affecting traffic north of Sampford Arundel.
Police were called to the crash involving a motorcycle around 10.45am.
The motorcycle rider and pillion passenger were both taken to Musgrove Park Hospital with minor injuries of the knee, hands and shoulder.
South Western Ambulance Service has confirmed the man and woman who were injured have been taken to hospital.
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